±âÀúÁúȯÀÌ ¾ø´Â ³ëÀÎȯÀÚ¿¡¼­ÀÇ Shigella boydii ±ÕÇ÷Áõ
Shigella boydii Bacteremia in an Ederly Patient with No Underlying Disease

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¿ì±¤¼÷(Woo Kwang-Sook) - µ¿¾Æ´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
ÃÖÀ縲(Choi Jae-Lim) - µ¿¾Æ´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
±èº¸¶÷(Kim Bo-Ram) - µ¿¾Æ´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
±èÁöÀº(Kim Ji-Eun) - µ¿¾Æ´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
±è°æÈñ(Kim Kyeong-Hee) - µ¿¾Æ´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
±èÁ¤¸¸(Kim Jung-Man) - µ¿¾Æ´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
ÇÑÁø¿µ(Han Jin-Yeong) - µ¿¾Æ´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç

Abstract

ÀÌÁú±Õ¿¡ ÀÇÇÑ ±ÕÇ÷ÁõÀº ±ØÈ÷ µå¹°¸ç ÁÖ·Î ¼Ò¾Æ¿¡¼­ ¹ß»ýÇÑ´Ù. ÀÌÁú±ÕÀº ÁÖ·Î ¼³»ç³ª À§Àå°ü¿¡ ±¹ÇÑ µÈ ¿°ÁõÀ» ÀÏÀ¸Å°¸ç±ÕÇ÷ÁõÀº ¸Å¿ì µå¹°´Ù. º» Áõ·Ê¿¡¼­´Â 2ÀÏ°£ÀÇ ¿À½É, ±¸Åä, ¿­°¨À» ÁÖ¼Ò·Î ³»¿øÇÑ 84¼¼ ȯÀÚ¿¡¼­ Shigella boydii¿¡ ÀÇÇѱÕÇ÷ÁõÀ» ¼­¼úÇÏ°í ÀÖ´Ù. ¸»ÃÊ Ç÷¾× ¹è¾ç °Ë»ç¿¡¼­ S. boydii°¡ ºÐ¸®µÇ¾ú°í 16S rDNA ¿°±â¼­¿­ºÐ¼®¿¡¼­µµ µ¿ÀÏ ¼Ò°ßÀ»º¸¿´´Ù. ±×·¯³ª ȯÀÚÀÇ ´ëº¯¼¼±Õ¹è¾ç °Ë»ç¿¡¼­´Â ±ÕÀÌ ºÐ¸®µÇÁö ¾È¾Ò´Ù. ȯÀÚ´Â °¨¼ö¼ºÀ» º¸ÀÎ ciprofloxacinÀ¸·Î Ä¡·á¸¦½ÃÀÛÇÏ¿´°í 14ÀÏ °úÁ¤ÀÇ ciprofloxacin Ä¡·á¸¦ °è¼Ó ÇÏ´Â ¹æħ ÇÏ¿¡ Åð¿øÇÏ¿´´Ù. ÀÌÁú±Õ¿¡ ÀÇÇÑ °¨¿°ÁõÀº º¸Åë ÀÚ°¡ ȸº¹ÀåÁúȯÀ» ÀÏÀ¸Å²´Ù. ÇÏÁö¸¸ ´ëº¯°ú Ç÷¾×¿¡¼­ µ¿½Ã¿¡ ºÐ¸®µÇ´Â °æ¿ì¿Í´Â ´Ù¸£°Ô Ç÷¾×¿¡¼­¸¸ ºÐ¸®µÇ´Â °æ¿ì ³ôÀº Ä¡»çÀ²°ú °ü·ÃÀÌ ÀÖ´Ù°í ¾Ë·ÁÁ® ÀÖ´Ù. µû¶ó¼­ ±Þ¼º ¿­¼º À§Àå°ü¿°À» ÁÖ¼Ò·Î ³»¿øÇÑ ¸é¿ª ÀúÇÏ È¯ÀÚ³ª ³ëÀο¡¼­´Â Shigella µîÀǺ´¿ø±ÕÀ» °ËÃâÀ» À§ÇÑ Ç÷¾× ¹è¾çÀÌ ²À ÇÊ¿äÇÏ´Ù.
Shigella bacteremia is rare, occurring mainly in children. Shigella species often cause diarrhea or gastrointestinal inflammation in humans and are rarely associated with bacteremia. This report describes an unusual case of Shigella boydii bacteremia in an 84-year-old patient visiting our hospital after experiencing nausea, vomiting, and febrile sensation for 2 days. Peripheral blood cultures revealed S. boydii and 16S rDNA sequence analysis produced the same result. However, the organism was not isolated from the patient¡¯s stool. She was started on ciprofloxacin, to which this organism is sensitive, and was subsequently discharged with instructions to complete a 14-day course of ciprofloxacin. Shigellosis is usually a self-limiting enteric disease. However, in contrast to its isolation from both blood and stool, isolation of the organism from blood only is associated with a high mortality rate. As is frequently pointed out, blood cultures should be obtained from elderly or immunocompromised patients with acute febrile gastroenteritis to detect infection caused by enteric pathogens, including Shigella.

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Bacteremia, Blood cultures, Shigella boydii
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DOI
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ICD 03
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